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Disease Knowledge Drug Updates
- Enbrel 25 mg powder and solvent for solution for injection
- Sustiva 50 mg, 100 mg and 200 mg Hard Capsules
- Sandostatin LAR
- Difflam Oral Rinse
- Teoptic 1% - Teoptic 2%
- Erythroped A 500 mg Tablets
- Enalapril 5mg Tablets
- Viskaldix Tablets
- Aricept Tablets
- Difflam Cream
- Alfentanil 500 micrograms/ml solution for injection
- Revlimid
- Benadryl Plus Capsules
- Diclomax Retard
- Voltarol Tablets
- Virgan
- DIXARIT (menopausal disorders)
- Rapiscan (regadenoson)
- Neurontin Capsules and Tablets
- Aprovel Film-Coated Tablets (sanofi-aventis Bristol-Myers Squibb SNC)
- Foradil
- Nystatin-Dome Suspension 100,000 I.U./ml
- Meningitec in pre-filled syringe
- Catapres Tablets 100mcg
- Kemadrin 5 mg Tablets
- SECTRAL 400mg tablets
- Sectral 100mg and 200mg
- Eucardic 25mg Tablets
- ALDOMET Tablets 250 mg
- Parvolex 200 mg/ml Concentrate for Solution for Infusion
- Mifegyne
- Pedea 5 mg/ml solution for injection
- Eucardic 12.5mg Tablets
- Qvar 100 Easi-Breathe
- Qvar 50 Easi-Breathe
- Eucardic 6.25mg Tablets
- Qvar MDI 50 micrograms
- Sonata 5 mg hard capsules
- PRO-EPANUTIN
- Xarelto 20mg film-coated tablets
Cystic Fibrosis
Please note - The Cystic Fibrosis Knowledge Centre is for Doctors and other Healthcare Professionals. Enter the Cystic Fibrosis Knowledge Centre.
Cystic Fibrosis (CF) is caused by a defect in a gene known as the cystic fibrosis transmembrane conductance regulator (CFTR) gene. This gene makes a protein that controls the movement of ions, such as chloride, and water, across cell membranes.
CF is caused by hundreds of different gene mutations. The most common mutation is delta F508, usually written as ΔF508.
Thick, sticky mucus causes most of the symptoms of CF. The most common symptoms of CF include:
- Persistent cough, often with phlegm
- Frequent lung infections
- Wheezing or shortness of breath
- Very salty-tasting skin
- Poor growth or weight gain despite a good appetite
- Greasy, bulky, foul-smelling stools Stomach pain and discomfort caused by too much gas in the intestines
- Dehydration
Because CF is a multisystem disease, treatment must be multidisciplinary, with a team of healthcare professionals providing comprehensive management of the patient.
Current therapy for CF is targeted at prevention and treatment of exacerbations. Care at the CF center includes inpatient as well as outpatient clinical care.
Enter the Cystic Fibrosis Knowledge Centre
What’s in the Cystic Fibrosis Knowledge Centre?
- Definition
- Causes of Cystic Fibrosis (CF)
- Physiologic Consequences
- Incidence and Prevalence
- Clinical Consequences
- Effects on the Respiratory System
- Effects on the Digestive system
- CF- related Diabetes Mellitus
- Effects on the Heart
- Other Effects of Cystic Fibrosis
- Early screening and Diagnosis
- Clinical Manifestation
- Multiple Organ Involvement
- Progression of Respiratory Clinical Features
- Complications of Lung Disease
- Other Symptoms Affected by CF
- Diagnostic Approach
- Lung Function Tests
- Spirometry Testing
- Pulmonary Function Tests
- Management of Cystic Fibrosis
- Nutritional Support
- Lung Management
- Management of the Digestive System
- Management of the Gallbladder and Liver
- Management of the Pancreas
- Prognosis
- Antibiotic Therapy
- Emerging Pathogens
- Anti-inflammatory Therapy
- Severe Disease
- Resources - FAQ
