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Diabetes

Please note - The Diabetes Knowledge Centre is for Doctors and other Healthcare Professionals. Enter the Diabetes Knowledge Centre.

The prognosis of patients with diabetes is improved by interventions that reduce HbA1C which is influenced by both fasting and postprandial blood glucose levels. Using basal insulin analogues to manage blood glucose levels in patients with Type 2 diabetes is beneficial for a number of reasons.

Diabetes Knowledge Centre

Postprandial glucose represents a major contribution to overall hyperglycaemia and is important in the improvement of glycaemic control.  Postprandial hyperglycaemia per se is also an independent risk factor for adverse cardiovascular outcomes and complications of diabetes.

The IDF guidelines are easily available, and assist physicians in the diagnosis and management of diabetes.

Consequently, postprandial hyperglycaemia is an important clinical target in the treatment of diabetes mellitus, as is now recognised in all major treatment guidelines.

Reducing postprandial blood glucose excursions in patients with diabetes requires that their blood insulin concentrations are increased rapidly in the early prandial setting. However, the absorption properties of subcutaneously administered soluble human insulin are not ideal for achieving this goal.

Both oral and insulin therapies are available for the treatment

Analogues of human insulin, such as insulin aspart, have been engineered for more rapid absorption through reduced self-association properties, enabling a more satisfactory re-creation of the prandial insulin response.

Enter the Diabetes Knowledge Centre

What’s in the Diabetes Knowledge Centre?

More Results Drugs Relating To diabetes
  • DDAVP
    ... and treatment of vasopressin-sensitive cranial diabetes insipidus; establishing renal concentration capacity. DDAVP Tablets: Treatment of vasopressin-sensitive cranial diabetes insipidus; treatment of post-hypophysectomy polyuria/ polydipsia. DDAVP/Desmopressin Injection: Cranial diabetes insipidus ...
  • Lisinopril 5 mg tablets
    ... Acute myocardial infarction Short-term (6 weeks) treatment of haemodynamically stable patients within 24 hours of an acute myocardial infarction. Renal complications of diabetes mellitus Treatment of renal disease in hypertensive patients with Type 2 diabetes mellitus and incipient nephropathy
  • Lisinopril 2.5mg Tablets
    ... Acute myocardial infarction Short-term (6 weeks) treatment of haemodynamically stable patients within 24 hours of an acute myocardial infarction. Renal complications of diabetes mellitus Treatment of renal disease in hypertensive patients with Type 2 diabetes mellitus and incipient nephropathy ...
  • JANUVIA Film-Coated Tablets
    JANUVIA is indicated in patients with type 2 diabetes mellitus to improve glycaemic control in combination with metformin when diet and exercise, plus metformin do not provide adequate glycaemic control. For patients with type 2 diabetes mellitus in whom use of a PPAR? agonist (i.e. a ...
  • EXUBERA
    ... for the treatment of adult patients with type 2 diabetes mellitus not adequately controlled with oral antidiabetic agents and requiring insulin therapy. EXUBERA is also indicated for the treatment of adult patients with type 1 diabetes mellitus, in addition to long or intermediate acting ...
  • HUMALOG
    For the treatment of adults and children with diabetes mellitus who require insulin for the maintenance of normal glucose homeostasis. HUMALOG, HUMALOG Pen or HUMALOG KwikPen is also indicated for the initial stabilisation of diabetes mellitus ...

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