ACUPAN, Nefopam, Tablet, Medicine and Disease information

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ACUPAN overview

Acupan is indicated for the relief of acute and chronic pain, including post-operative pain, dental pain, musculo-skeletal pain, acute traumatic pain and cancer pain.

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Related DrugsDrug Details

ACUPAN

Drug Class Description :

Benzoxazocines (non-opioid analgesics).

Generic Name :

Nefopam

Drug description :

Nefopam Hydrochloride 30 mg.

Presentation :

Tablet

Indications :

Acupan is indicated for the relief of acute and chronic pain, including post-operative pain, dental pain, musculo-skeletal pain, acute traumatic pain and cancer pain.

Adult Dosage :

Dosage may range from 1 to 3 tablets three times daily depending on response. The recommended starting dosage is 2 tablets three times daily.

Child Dosage :

Since Acupan has not been evaluated in children, no dosage recommendation can be given for patients under 12 years

Elderly Dosage :

Elderly patients may require reduced dosage due to slower metabolism. It is strongly recommended that the starting dose does not exceed one tablet three times daily as the elderly appear more susceptible to, in particular, the CNS side effects of Acupan and some cases of hallucinations and confusion have been reported in this age group.

Contra Indications :

Acupan is contra-indicated in patients with a history of convulsive disorders and should not be given to patients taking mono-amine-oxidase (MAO) inhibitors.

Special Precautions :

The side effects of Acupan may be additive to those of other agents with anticholinergic or sympathomimetic activity. It should not be used in the treatment of myocardial infarction since there is no clinical experience in this indication. Hepatic and renal insufficiency may interfere with the metabolism and excretion of nefopam. Acupan should be used with caution in patients with, or at risk of, urinary retention. Rarely a temporary, harmless pink discolouration of the urine has occurred.

Interactions :

Caution should be exercised when nefopam is administered concurrently with tricyclic antidepressants.

Adverse Reactions :

Nausea
nervousness
dry mouth and light-headedness
urinary retention
hypotension
syncope
palpitations
gastrointestinal disturbances (including abdominal pain and diarrhoea)
dizziness
paraesthesia
convulsions
tremor
confusion
hallucination
angioedema and allergic reactions may occur.
Less frequently
vomiting
blurred vision
drowsiness
sweating
insomnia
headache and tachycardia have been reported.

Manufacturer :

Meda Pharmaceuticals Ltd

Drug Availability :

(POM)

Drug Updated :

23 June 2009

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