Warfarin, Generic Monitor international normalised ratio (INR) on a regular basis., Tablets, scored, warfarin sodium 1m, Medicine and Disease information

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Warfarin overview

Thromboembolic conditions.

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Warfarin

Drug Class Description :

Coumarin anticoagulants.

Generic Name :

Generic Monitor international normalised ratio (INR) on a regular basis.

Drug description :

Tablets.

Presentation :

Tablets, scored, warfarin sodium 1mg (brown), 3mg (blue), 5mg (pink). Available from APS, Cox, Hillcross, Lagap, Norton, Regent.

Indications :

Thromboembolic conditions.

Adult Dosage :

Initially 10mg daily, adjust daily according to INR.

Contra Indications :

Haemorrhagic conditions. Pregnancy. Peptic ulcer, severe hypertension, bacterial endocarditis.

Special Precautions :

Impaired renal or hepatic function. Within 24 hours of surgery or labour. Weight changes, acute illness, vitamin K deficiency.

Interactions :

Aspirin, NSAIDs, oral hypoglycaemics, sulphonamides, amiodarone, quinidine, propafenone, antibiotics (including rifamycins, cefamandole (cephamandole), chloramphenicol, ciprofloxacin, co-trimoxazole, erythromycin, metronidazole, ofloxacin, sulphonamides), antifungals, antivirals, phenformin, cimetidine, drugs affecting liver enzymes, corticosteroids, imidazole antifungals, tamoxifen. Alcohol. Anabolic steroids, colestyramine (cholestyramine), antiepileptics, simvastatin, thyroxine (levothyroxine), vitamin K.

Adverse Reactions :

Haemorrhage. Alopecia, rash, diarrhoea, fall in haematocrit. Skin necrosis, jaundice, hepatic dysfunction. Nausea, vomiting, pancreatitis.

Drug Availability :

(POM)

Drug Updated :

17 June 2009

Related Drugs - Anticoagulants, antithrombotics & fibrinolytics

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