Nystatin-Dome Suspension 100,000 I.U./ml, nystatin, Oral suspension, Medicine and Disease information

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Nystatin-Dome Suspension 100,000 I.U./ml overview

The prevention and treatment of candidal infections of the oral cavity, oesophagus and intestinal tract. The suspension provides effective prophylaxis against oral candidosis in those born of mothers with vaginal candidosis.

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Nystatin-Dome Suspension 100,000 I.U./ml

Drug Class Description :

Antifungals.

Generic Name :

nystatin

Drug description :

Each ml contains 100,000 I.U. Nystatin BP.

Presentation :

Oral suspension

Indications :

Adult Dosage :

For the treatment of denture sores, and oral infections in adults caused by candidas albicans. 1ml of the suspension should be dropped into the mouth four times daily; it should be kept in contact with the affected areas as long as possible.

For the treatment of intestinal candidosis 5ml of the suspension should be dropped into the mouth four times daily.

For prophylaxis a total daily dosage of 1 million units has been found to suppress the overgrowth of candidas albicans in patients receiving broad-spectrum antibiotic therapy.

Administration should be continued for 48 hours after clinical cure to prevent relapse.

Child Dosage :

In intestinal and oral candidosis (thrush) in infants and children 1ml should be dropped into the mouth four times a day. The longer the suspension is kept in contact with the affected area in the mouth before swallowing, the greater will be its effect.

Administration should be continued for 48 hours after clinical cure to prevent relapse.

For prophylaxis in the newborn the suggested dose is 1ml once daily.

Elderly Dosage :

No specific dosage recommendations or precautions.

Contra Indications :

Contra-indicated in patients with a history of hypersensitivity to any of the components.

Special Precautions :

Nystatin Oral Suspension BP contains sugar.

Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.

Nystatin oral preparations should not be used for treatment of systemic mycoses.

The label states the following warnings:-

Shake well before use.

Do use if seal is broken.

This product should not be diluted.

Store in a cool place. Avoid freezing.

Protected from light.

Interactions :

Not known.

Adverse Reactions :

Nystatin is generally well tolerated by all age groups, even during prolonged use. Rarely hypersensitivity, oral irritation or sensitisation may occur. Nausea has been reported occasionally during therapy.

There have been reports of rash (including urticaria) and rarely Stevens-Johnson syndrome has been reported.

Large doses of nystatin could cause face oedema, vomiting, diarrhoea and gastrointestinal distress.

Manufacturer :

Sandoz Limited

Drug Availability :

(POM)

Drug Updated :

15 February 2012

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