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- Fostair 100/6 inhalation solution
- Epanutin capsules 25, 50 and 100mg
- Eprex 2000, 4000 and 10000 IU/ml solution for injection in pre-filled syringe
- FemSeven Conti
- Epanutin 300mg hard capsules
- Bedranol 80mg SR Capsules
- Bedranol 160mg SR Capsules
- Betim 10mg Tablets
- Carbo-Dome Cream
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- Rivotril 0.5 mg and 2 mgTablets
- Rivotril Ampoules
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- Witch Doctor ® 81.5%w/w Gel
- Levetiracetam Actavis 1,000 mg film-coated tablets
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- Levetiracetam Actavis 500 mg film-coated tablets
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- Lidocaine Hydrochloride Injection BP 1% w/v plastic ampoules
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- Anadin Ultra Double Strength 400mg Capsules/Anadin LiquiFast 400mg Capsules
- Calcipotriol Scalp Solution
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- Lescol (fluvastatin* sodium) 20 mg and 40 mg capsules
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- VALTREX Tablets 250mg
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- Water for Injections
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- NovoRapid 100 U/ml in a vial, NovoRapid Penfill 100 U/ml, NovoRapid FlexPen 100 U/ml, NovoRapid FlexTouch 100 U/ml
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- Natecal D3 Chewable Tablets
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Peptides (antibiotics).
Polymyxin B sulphate, bacitracin zinc - eye infections
Polymyxin B Sulphate 10,000 IU Bacitracin zinc 500 IU
Ointment
Topical antibacterial agent. Polyfax Ointment is indicated for the treatment of infected wounds, burns, skin grafts, ulcers, pyoderma, sycosis barbae, impetigo, and in secondarily infected skin lesions of scabies, pediculosis, tinea pedis and contact and allergice dermatitis.
ADULTS
Polyfax Ointment should be applied thinly over the affected area, which is best left exposed. Two or more applications a day may be necessary, depending on the severity of the condition.
CHILDREN
As for adults.
No specific studies have been carried out in the elderly, however, it may be advisable to monitor renal function in these patients and if there is any impairment then caution should be exercised.
Hypersensitivity to bacitracin, Polymyxins or cross-sensitising substances.
The following statements take into account the possibility that the constituent drugs of Polyfax Ointment may be absorbed to a significant degree after topical application. However, the normal use of Polyfax is unlikely to present any risk of systemic toxicity unless the application were excessive e.g. more than 200 g per day in adults or proportionately less in children and in patients with compromised renal function.
Following significant systemic absorption polymyxin B sulphate and bacitracin zinc have nephrotoxic potential and polymixin B sulphate has neurotoxic potential.
As with all antibacterial preparations prolonged use may result in the overgrowth of non-susceptible organisms including fungi.
Following significant systemic absorption, polymyxin B can intensify and prolong the respiratory depressant effects of neuromuscular blocking agents.
Allergic reactions following topical application of polymyxin B and bacitracin zinc have rarely been reported.
Anaphylactic reactions have been reported, as rare events, following topical application of zinc bacitracin.
Pliva Pharma Ltd
(POM)
08 June 2009





