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Polyfax Ointment overview
Topical antibacterial agent. Polyfax Ointment is indicated for the treatment of infected wounds, burns, skin grafts, ulcers, pyoderma, sycosis barbae, impetigo, and in secondarily infected skin lesions of scabies, pediculosis, tinea pedis and contact and allergice dermatitis.
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Related DrugsDrug Details
Polyfax Ointment
Drug Class Description :

Peptides (antibiotics).

Generic Name :

Polymyxin B sulphate, bacitracin zinc - eye infections

Drug description :

Polymyxin B Sulphate 10,000 IU Bacitracin zinc 500 IU

Presentation :

Ointment

Indications :

Topical antibacterial agent. Polyfax Ointment is indicated for the treatment of infected wounds, burns, skin grafts, ulcers, pyoderma, sycosis barbae, impetigo, and in secondarily infected skin lesions of scabies, pediculosis, tinea pedis and contact and allergice dermatitis.

Adult Dosage :

ADULTS

Polyfax Ointment should be applied thinly over the affected area, which is best left exposed. Two or more applications a day may be necessary, depending on the severity of the condition.

CHILDREN

As for adults.

 

 

Elderly Dosage :

No specific studies have been carried out in the elderly, however, it may be advisable to monitor renal function in these patients and if there is any impairment then caution should be exercised.

Contra Indications :

Hypersensitivity to bacitracin, Polymyxins or cross-sensitising substances.

Special Precautions :

The following statements take into account the possibility that the constituent drugs of Polyfax Ointment may be absorbed to a significant degree after topical application. However, the normal use of Polyfax is unlikely to present any risk of systemic toxicity unless the application were excessive e.g. more than 200 g per day in adults or proportionately less in children and in patients with compromised renal function.

Following significant systemic absorption polymyxin B sulphate and bacitracin zinc have nephrotoxic potential and polymixin B sulphate has neurotoxic potential.

As with all antibacterial preparations prolonged use may result in the overgrowth of non-susceptible organisms including fungi.

Interactions :

Following significant systemic absorption, polymyxin B can intensify and prolong the respiratory depressant effects of neuromuscular blocking agents.

Adverse Reactions :

Allergic reactions following topical application of polymyxin B and bacitracin zinc have rarely been reported.

Anaphylactic reactions have been reported, as rare events, following topical application of zinc bacitracin.

Manufacturer :

Pliva Pharma Ltd

Drug Availability :

(POM)

Drug Updated :

08 June 2009

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