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Zovirax Eye Ointment overview

Treatment of herpes simplex keratitis.

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Related DrugsDrug Details
Zovirax Eye Ointment
Drug Class Description :

Antivirals.

Generic Name :

Aciclovir

Drug description :

Aciclovir 3.0% W/W

Presentation :

Ophthalmic Ointment

Indications :

Treatment of herpes simplex keratitis.

Adult Dosage :

Topical administration to the eye.

1cm ribbon of ointment should be placed inside the lower conjunctival sac five times a day at approximately four hourly intervals, omitting the night time application. Treatment should continue for at least 3 days after healing is complete.

Child Dosage :

As for adults

Elderly Dosage :

As for adults

Contra Indications :

Zovirax eye ointment is contra-indicated in patients with a known hypersensitivity to aciclovir or valaciclovir, or any of the excipients.

Special Precautions :

Patients should avoid wearing contact lenses when using Zovirax Eye Ointment.

Interactions :

No clinically significant interactions have been identified.

Adverse Reactions :

Adverse reactions are listed below by MedDRA body system organ class and by frequency.

The frequency categories used are:

Very common

GREATER-THAN OR EQUAL TO (8805) 1/10,

Common

GREATER-THAN OR EQUAL TO (8805) 1/100 and < 1/10,

Uncommon

GREATER-THAN OR EQUAL TO (8805) 1/1,000 and <1/100,

Rare

GREATER-THAN OR EQUAL TO (8805) 1/10,000 and <1/1,000,

Very rare

<1/10,000.

Clinical trial data have been used to assign frequency categories to adverse reactions observed during clinical trials with aciclovir 3% ophthalmic ointment. Due to the nature of the adverse events observed, it is not possible to determine which events were related to the administration of the drug and which were related to the disease. Spontaneous reporting data has been used as a basis for allocating frequency for those events observed post-marketing.

Immune system disorders:

Very rare:

Immediate hypersensitivity reactions including angioedema and urticaria.

Eye disorders:

Very common:

Superficial punctate keratopathy.

This did not necessitate an early termination of therapy and healed without apparent sequelae.

Common:

Transient mild stinging of the eye occurring immediately following application, conjunctivitis.

Rare:

Blepharitis.

Manufacturer :

GlaxoSmithKline UK

Drug Availability :

(POM)

Drug Updated :

29 March 2012

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