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Abbreviations

The abbreviations used in this training programme are listed and explained in the following table.

Abbreviations
6-SMT 6-sulfatoxymelatonin
AE Adverse event
AFS Ease of awakening from sleep
ASPS Advanced sleep-phase syndrome
ATC Anatomical therapeutic chemical name
AUC  Area under the curve
BFW Behaviour following wakefulness
BP Blood pressure
BWSQ  Benzodiazepine Withdrawal Symptom Questionnaire
BZD Benzodiazepine
CBT Cognitive–behavioural therapy
CFF Critical flicker fusion
CGI Clinical global improvement
Cmax Maximum concentration
CNS Central nervous system
CSF Cerebrospinal fluid
DCSAD Diagnostic Classification of Sleep and Arousal Disorders
DIMS Disorders of initiating and maintaining sleep
DOES Disorders of excessive sleep
DSHEA FDA Dietary Supplement Health and Education Act
DSM-IV-TR Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition text revision
DSPS Delayed sleep-phase syndrome
DWAPSO Duration of wake prior to sleep onset
ECG Electrocardiograph
EEG Electroencephalograph
EMG Electromyography
EOG Electro-oculogram
F1 First generation offspring
FDA Food and Drugs Administration – US drug regulation authority
GP General practitioner
GTS Ease of getting to sleep
HCRT Hypocretin (orexin)
i.p. Intraperitoneal
ICD-10 International Classification of Diseases
ICSD International Classification of Sleep Disorders
INN International non-proprietary name
IR Immediate release
LD Lethal dose
LED Light emitting diodes
LH Lateral hypothalamus
LSEQ Leeds Sleep Evaluation Questionnaire
MCRT Multiple choice reaction time
MDD Major depressive disorder
MMSE Mini mental state examination
MOP Methoxypsoralen
MT Melatonin receptor
NICE National Institute of Health and Clinical Excellence
NREM Non-rapid eye movement
NTP National toxicity program
OC Outer canthi
OTC Over-the-counter
PR Prolonged release
PSG Polysomnography
PSQI Pittsburgh Sleep Quality Index
QOD Quality of the day
QOL Quality of life
QON Quality of a patient’s sleep the previous night
QOS Quality of sleep
REM Rapid eye movement
SAD Seasonal affective disorders
SAE Serious adverse event
SCN Suprachiasmatic nucleus
SEMs Slow eye movements
SHQ Sleep history/habits questionnaire
SSRI Selective serotonin reuptake inhibitor
SWA Slow wave activity
SWS Slow wave sleep
T1/2 Half-life
TCA Tricyclic antidepressants
Tmax Time to maximum concentration
TMN Tuberomammillary nucleus
VAS Visual analogue scale
VLPO Ventrolateral preoptic nucleus
WASO Wake after sleep onset
'z'-drug zolpidem, zopiclone, zaleplon
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