Mode of Action | Pharmacology | Pharmacokinetics | Safety & Tolerability | Receptor Affinity | Hardness | Duration | First Dose Success | Reliability | Fast Onset | PERT | ED & Diabetes | ED & Hypertension | ED & Dyslipidemia | ED & Metabolic Syndrome | ED & Radical Prostatectomy | ED & The Role of Female Partner

Treatment Options

Levitra - Receptor Affinity

Levitra has a very high receptor affinity compared to other PDE5 inhibitors. This allows for less substance needed to reach the same effects. Less substance may also decrease the risk of possible side effects.

Levitra has a higher inhibitory potential than Viagra® or Cialis®

PDE-5 inhibitorIC50 (nmol/L)
Levitra (vardenafil) 0.1–0.7
Viagra (sildenafil) 3.5–8.5
Cialis (tadalafil) 0.9–6.7

IC50, PDE-5 inhibitor concentration causing 50% inhibition of PDE-5 activity

References:
1. Gresser U et al. Eur J Med Res 2002; 7: 435–46;
2. Saenz de Tejada I et al. Int J Impot Res 2001; 13: 282–90.

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